hrp0084p1-114 | Puberty | ESPE2015
Kolodkina Anna
, Kareva Maria
, Kalinchenko Natalia
, Raygorodskaya Nadezhda
, Malievsky Oleg
, Fidelina Olga
, Vasilyev Evgeny
, Petrov Vasily
, Naumova Maria
, Tiulpakov Anatoly
Background: To date at least 30 genes are known to be associated with idiopathic hypogonadotropic hypogonadism (IHH). Analysis of all these gene candidates by Sanger sequencing would be expensive, labour-intensive and time-consuming. Recent introduction of next-generation sequencing (NGS) enables simultaneous analysis of multiple gene targets making it an attractive approach in such conditions as IHHObjective and hypotheses: To study the spectrum of mole...