hrp0095p1-436 | Diabetes and Insulin | ESPE2022
Kostopoulou Eirini
, Efthymia Katsa Maria
, Ioannidis Anastasios
, Foti Maria
, Dimopoulos Ioannis
, Spiliotis Bessie
, Paola Rojas Gil Andrea
Introduction: Type 1 diabetes mellitus (T1DM) is characterized by insulin-producing pancreatic β-cells loss. Apo1/Fas, a glycosylated surface protein, is implicated in maintaining homeostasis of the immune system. Cytokeratin-18 (cCK-18) is a predictive marker of liver disorders in T2DM. Intercellular adhesion molecule-1 (ICAM-1) is considered a candidate gene for susceptibility to diabetes mellitus. Aim: To investigate the possible role of Apo1/Fas, cCK-...