hrp0092rfc5.2 | Thyroid | ESPE2019

Ultrasound Features of Multinodular Goiter in DICER1 Syndrome

Niedziela Marek , Muchantef Karl , Foulkes William D

Background: DICER1 syndrome is caused by germline mutations in the DICER1 gene. It is associated with a wide spectrum of benign and malignant neoplasms, which are accompanied by specific somatic mutations in DICER1. Multinodular goiter (MNG) is a common clinical feature of DICER1 syndrome in children and adults; the thyroid ultrasound (US) features of MNG in the setting of DICER1 syndrome have not been widely reported.<...