hrp0095p1-433 | Bone, Growth Plate and Mineral Metabolism | ESPE2022
, Tridjaja Bambang
, B Pulungan Aman
, RL Batubara Jose
, Soesanti Frida
Background: Infantile hypophosphatasia (HPP) is an ultra-rare condition that may lead to debilitating morbidity and mortality. The prevalence of HPP in Indonesia is unknown. Enzyme replacement therapy or asfotase alfa, a bone-targeted recombinant alkaline phosphatase, can improve clinical outcome and prognosis of the patients, particularly those with severe type of HPP. The complications of HPP may be life-threatening and contribute to higher mortality in youn...