hrp0084p1-27 | Diabetes | ESPE2015
Barrios Vicente
, Burgos-Ramos Emma
, Canelles Sandra
, Rodriguez Amaia
, Gomez-Ambrosi Javier
, Chowen Julie A
, Fruhbeck Gema
, Argente Jesus
Background: Skeletal muscle is the largest tissue involved in the insulin-stimulated disposal of glucose, with its size being controlled by hormonal status, among other factors. Leptin plays a primary role in the regulation of glucose homeostasis with a substantial degree of insulin and leptin cross-talk in muscle. However, the relationship between the leptins central effects on insulin sensitivity in muscle and associated structural changes remain unclear.<p class="...