hrp0082p3-d2-784 | Fat Metabolism & Obesity (1) | ESPE2014
von Schnurbein Julia
, Fischer-Posovszky Pamela
, Garg Abhimanyu
, Wabitsch Martin
Background: Congenital generalized lipodystrophy (CGL) is characterized by the absence of most adipose tissue at birth due to an adipocyte differentiation block. For several forms of CGL, the underlying mutation and pathophysiological pathway has been identified. However, for many cases the genetic cause is still unknown.Objective and hypotheses: We report a patient with CGL who showed a complete absence of fat apart from protective fat pads in a postnat...