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hrp0086p2-p705 | Endocrinology and Multisystemic Diseases P2 | ESPE2016

Endocrinological Disorders in Children with Neurofibromatosis Type 1 and Optic Pathway Gliomas

Nacca Raffaella , Scillipoti Martina , Grandone Anna , Santoro Claudia , Cinalli Giuseppe , Cirillo Mario , Cioffi Daniela , Luongo Caterina , Del Giudice Emanuele Miraglia , Perrotta Silverio , Perrone Laura

Background: Children with neurofibromatosis type 1 (NF1) have an increased risk of developing optic pathway gliomas (OPGs) during childhood. Although these tumors usually have a benign course, some cases result in significant clinical symptoms, including endocrinological disorders.Objective and hypotheses: The aim of this study is to evaluate the endocrinological complications of OPGs involving the chiasm in children with NF1.Metho...

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hrp0092rfc11.2 | Pituitary, Neuroendocrinology and Puberty Session 2 | ESPE2019

Prevalence and Predicting Factors of Endocrine Dysfunction in Children with NF1 and Optic Gliomas

Santoro Claudia , Perrotta Silverio , Scilipoti Martina , Cirillo Mario , Quaglietta Lucia , Cinalli Giuseppe , Cioffi Daniela , Di Iorgi Natascia , Gallizia Annalisa , Maghnie Mohamad , Parpagnoli Maria , Messa Federica , Vannelli Silvia , De Sanctis Luisa , Marzuillo Pierluigi , del giudice Emanuele Miraglia , Grandone Anna

Introduction:Up to 20% of children with neurofibromatosis type 1 (NF1) develops low-grade optic pathway gliomas(OPGs) that can result in neuroendocrinopathy.The aim of the study was to identify prognostic factors for developing neuroendocrinopathies in patients with NF1 and OPGs before any treatment.Methods: Records of 117 children with NF1 and OPGs followed at 4 Italian centers between 1997-20...

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ESPE Abstracts

Endocrinological Disorders in Children with Neurofibromatosis Type 1 and Optic Pathway Gliomas

Prevalence and Predicting Factors of Endocrine Dysfunction in Children with NF1 and Optic Gliomas

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