hrp0098rfc2.1 | Bone, Growth Plate and Mineral Metabolism | ESPE2024

Bone and Body Composition after one year of Vosorotide treatment in children with Achondroplasia: a longitudinal prospective study.

Angelelli Alessia , Elsa Maria Allegri Anna , Tedesco Caterina , Maiorano Nadia , Zucconi Alice , Repetto Agnese , Gizzi Gilda , Napoli Flavia , Casalini Emilio , Fava Daniela , Mohamad Maghnie , Di Iorgi Natascia

Background: Bone and body composition data in Achondroplasia (Ach) treated or not with vosorotide are lacking.Aim: To assess longitudinally body composition and bone markers in children with Ach during Vosorotide treatment (V-Tx).Method: Twenty-one patients (F=11, M=10) underwent DXA evaluation before (T0) and after 12 months of V-Tx (T12): bone mineral density-BMD (g/cm2</sup...