hrp0095p1-264 | Fat, Metabolism and Obesity | ESPE2022

Triglyceride–glucose–alanine aminotransferase index as a novel and superior predictor for non-alcoholic fatty liver disease in children and adolescents

Seo Yoon Jong , Gyeol Kim Bit , Tae Hwang Il

Background: Insulin resistance, non-alcoholic fatty liver disease (NAFLD), and metabolic syndrome (MetS) are strongly correlated with each other. Triglyceride and glucose (TyG) index, a simple and useful insulin resistance surrogate marker, has recently been reported to be superior in predicting NAFLD in adults.Objects: We evaluated the usefulness of TyG–alanine aminotransferase (ALT) for detecting NAFLD and compar...

hrp0095p1-464 | Fat, Metabolism and Obesity | ESPE2022

Triglyceride glucose index is associated with the severity of ultrasonographic fatty liver indicator in pediatric non-alcoholic steatohepatitis

Gyeol Kim Bit , Seo Yoon Jong , Tae Hwang Il

Background: Triglyceride glucose (TyG) index is known as a reliable insulin resistance surrogate marker to identify non-alcoholic fatty liver disease (NAFLD). Ultrasound fatty liver indicator (US-FLI) is proposed as a non-invasive, semi-quantitative method for predicting hepatitis in children with NAFLD and may reflect the severity of liver histological changes. US-FLI ≥4 has been suggested as a predictive finding for severe NASH. US-FLI correlates signific...