ESPE Abstracts

Background: Hypoglycemia in children is common but can indicate serious underlying conditions. Previous research has shown low rates of complete diagnostic evaluations for hypoglycemia in pediatric emergency rooms. This may be due to the complexity and time-consuming nature of the required workup and a lack of knowledge about the incidence of serious hypoglycemic disorders in children. This study aims to assess the effectiveness of an intervention to improve t...

Background: Phosphoglucomutase 1 (PGM-1) deficiency is a congenital disorder of glycosylation caused by an impairment of glucose-1-phosphate and glucose-6-phosphate interconversion.The clinical phenotype of PGM1 deficiency is variable and includes several endocrine manifestations such as recurrent hypoglycemia and short stature, which may be associated with the decreased levels of growth hormone (GH), insulin like growth factor-1 (IGF1) ...