hrp0098p1-139 | Fat, Metabolism and Obesity 2 | ESPE2024

The effect of pharmacotherapy compared to lifestyle intervention on body composition in children and young people managed within a multidisciplinary weight management service

Dixon Hannah , Apperley Louise , Senniappan Senthil , Parkinson Jennifer

Introduction: Children and adolescents with a body mass index (BMI) greater than the 98th centile are at an increased risk of complications including cardiovascular and liver disease and type 2 diabetes mellitus. Currently, lifestyle modification is the first line intervention. Pharmacotherapy, such as liraglutide and semaglutide, has recently been licensed for adolescents greater than 12 years of age. This study aimed to compare the impact of pharmacotherapy ...