hrp0092p1-160 | Adrenals and HPA Axis (1) | ESPE2019

Serum fetuin-A and insulin levels in classic congenital adrenal hyperplasia

Kurnaz Erdal , Çetinkaya Semra , Özalkak Servan , Bayramoglu Elvan , Demirci Gülsah , Öztürk Hasan Serdar , Erdeve Senay Savas , Aycan Zehra

Background: Androgens play a pivotal role in non-reproductive tissues, such as the kidney, heart, and liver, as well as the pancreas. Since the androgen receptor is expressed in pancreas and liver cells, this raises the possibility that excess testosterone results in insulin hypersecretion, and in fetuin-A, a protein produced in the liver. However, whether fetuin-A and insulin levels are affected by androgens in classic congenital adrenal hyperplasia (CAH) due...