hrp0095p1-469 | Fat, Metabolism and Obesity | ESPE2022

Triglyceride-glucose-alanine aminotransferase index is associated with the severity of transient elastography in pediatric non-alcoholic steatohepatitis

Seo Yoon Jong , Tae Hwang Il , Hee Yi Kyung

Background: The triglyceride glucose (TyG) index is significantly associated with the presence of nonalcoholic fatty liver disease (NAFLD) and is a reliable insulin resistance (IR) surrogate marker. Alanine aminotransferase (ALT) has been commonly used to reflect liver inflammation and liver damage in patients with chronic liver diseases, including NAFLD. Transient elastography (TE) uses pulsed echo ultrasound to measure the hardness of the liver, showing exce...

hrp0092p3-172 | Growth and Syndromes (to include Turner Syndrome) | ESPE2019

Pure Gonadal Dysgenesis with Partial Testicular Development Associated with Turner Syndrome with SRY

Hee Yi Kyung , Kim Eun Young , Han Heon Seok

Turner syndrome is the most common chromosomal disorder in girls. They present classically short stature and delayed puberty. Turner girls with 45,X karyotype show normal female external genitalia. But Turner patients containing 45,X/46,XY mosaicism, or Sex-determining Region Y(SRY) gene may have mixed gonadal dysgenesis with various external sexual differentiation or pure gonadal dysgenesis. Existence of Y chromosome particles in Turner syndrome implies that they have risk of...

hrp0092p1-174 | Bone, Growth Plate and Mineral Metabolism (1) | ESPE2019

The Optimal Dosage of Vitamin D Supplement for Vitamin D deficiency in Korean Children and Adolescents

Yang Seung , Hee Yi Kyung , Kim Eun Young , Hwang Il Tae

Purpose: Vitamin D deficiency (VDD) is very common nowadays in children as well as in adults, probably due to decreased exposure to sunlight. In Korea, the prevalence of VDD was 47% in teenage boys and 65% in teenage girls. However, the optimal dosage regimen for correcting deficiency is unknown. We investigate the change of serum 25(OH) vitamin D concentration according to the treatment dosage and duration in VDD.Methods...

hrp0094p2-171 | Fat, metabolism and obesity | ESPE2021

Association of calprotectin with obesity in prepubertal children

Yoon Jong Seo , Young Kim Eun , Hee Yi Kyung , Suk Shim Young , Hwang IL Tae ,

Background: Perturbation of inflammation is critically linked to nutrient metabolic pathways and obesity-associated complications, such as insulin resistance and type 2 diabetes (T2DM). The S100 family of proteins, including S100A8/A9 (calprotectin), have been implicated in disease pathogenesis and investigated as potential markers of inflammation. In adults, increased circulating levels of calprotectin have been reported in obesity-related chronic low-grade i...

hrp0086p1-p484 | Fat Metabolism and Obesity P1 | ESPE2016

Fetuin-A as an Alternative Marker for Insulin Resistance and Cardiovascular Risk in Prepubertal Children

Joung Oh Yeon , Hee Yi Kyung , Jae Kang Min , Woo Baek Joon , Yang Seung , Tae Hwang Il

Background: Fetuin-A plays a role in insulin resistance and cardiovascular disease.Objective and hypotheses: The aim of present study was to determine the relation between fetuin-A levels and caridiometabolic risk factors and to investigate effect of serum fetuin-A to insulin sensitivity indices for determining whether fetuin-A is additional marker of insulin resistance in prepubertal children.Method: Ninety-nine prepubertal Korean...