hrp0082p3-d2-716 | Diabetes (1) | ESPE2014

Uptake of a Novel Tool to Adjust Insulin Boluses, Based on CGM Trend Arrows and Insulin Sensitivity (Trend Arrow Adjustment Tool); in Children with Type 1 Diabetes, Who are Using Insulin Pump Therapy and Continuous Glucose Monitoring

Heffernan Emmeline , Lawson Margaret

Background: Real-time CGM data includes ‘trend arrows’ which indicate when the blood glucose is rapidly falling or rising thus enabling the pump user to make immediate adjustments in insulin delivery to prevent subsequent low or high blood sugars. However, effective strategies for adjusting insulin boluses based on CGM trend arrows are lacking. Previous studies recommended that boluses be adjusted based on trend arrows using a standard 10–20% increase/decrease o...

hrp0082p3-d2-890 | Perinatal and Neonatal Endocrinology (1) | ESPE2014

A Novel Mutation Causing Pseudohypoaldosteronsim

Heffernan Emmeline , Abid Noina , McKee Shane

Background: We present a case of a neonate with life threatening hyponatraemia and hyperkalaemia, due pseudohypoaldosteronism, found to be caused by a novel mutation.Objective and hypotheses: An 8-day-old girl presented with a short history of poor feeding and vomiting. She was born at term, to consanguineous parents. She was severely shocked and required fluid resuscitation. She had profound hyponatraemia and hyperkalaemia. She was admitted to PICU with...

hrp0084p2-271 | Diabetes | ESPE2015

Evaluation of a Novel Tool to Adjust Insulin Boluses Based on Continuous Glucose Monitoring Trend Arrows and Insulin Sensitivity (Trend Arrow Adjustment Tool©) in Children and Youth with Type 1 Diabetes Using Insulin Pump Therapy

Heffernan Emmeline , Lawson Margaret , Bradley Brenda , Courtney Jennilea , Richardson Christine

Background: Continuous glucose monitoring (CGM) measures interstitial glucose and displays trend arrows, showing the direction and rate of change in glucose. Trend arrows allow the child/youth to take action to prevent hyper- and hypoglycaemia. Effective strategies for adjusting insulin for trend arrows are lacking. The JDRF CGM Study Group recommended a 10–20% increase/decrease in the insulin dose. However, the bolus dose is dependent on amount of food to be consumed and...