hrp0089p2-p001 | Adrenals and HPA Axis P2 | ESPE2018
Agnani Helena
, Houang Muriel
, Egether Thibaut
, Netchine Irene
, Lamaziere Antonin
Background: To diagnose non classical congenital adrenal hyperplasia (NCCAH) and adrenal insufficiency (AI), current guidelines recommend ACTH test. Cutoffs for 17 hydroxyprogesterone (17OHP) and cortisol are derived from immunoassays values. Thanks to a recently developed and validated mass spectrometry approach (LC-MS/MS) we routinely quantify simultaneously 16 circulating steroids and we are able to speculate on new cut off values and uses.<p class="abs...