ESPE Abstracts

While it has been established that within the first 4 months of life there is an absence of the circadian rhythm guiding cortisol secretion, it remains unclear if a random serum cortisol (rSC) level is useful in diagnosing neonatal primary adrenal insufficiency (PAI). The objective of this study is to determine the utility of rSC in determining PAI within the first 4 months of life. This is a retrospective chart review of subjects who had rSC collection and high dose cosyntrop...

It has been established that a random growth hormone (rGH) level can be obtained and is useful within the first 28 days of life for establishing a diagnosis of congenital growth hormone deficiency (cGHD). However, it remains unclear if weight-for-length (WfL), a surrogate for adiposity, impacts these levels, similar to how body mass index in older subjects impacts peak growth hormone levels derived from provocation testing. The objective of this study is to determine the impac...