hrp0084np1.2 | New Perspective Session 1 | ESPE2015

Optogenetic Control of Neuroendocrine Hormone Secretion

Herbison Allan

Optogenetics represents a powerful new approach to modulate the activity of excitable cells in the body. Based upon the ability of specific wavelengths of light to activate newly discovered and engineered opsin-based receptors, optogenetics can be used to control the activity of cells with very high temporal resolution. Opsin-based receptors, most often channelrhodopsin (ChR), need to be expressed selectively in the cell type under investigation. This is achieved by generating...