hrp0098p2-350 | Late Breaking | ESPE2024

The genetic and clinical aspects of 10 patients with GH-IGF-1 axis gene variants

Huang Xiaozhen , Chen Ruimin

Objective: This study analyzed ten short stature patients with growth hormone-insulin-like growth factor-1 (GH-IGF-1) axis gene variants, and aim ed to explore both clinical and genetic characteristics, as well as the recombinant human growth hormone (rhGH) treatment response through a review of the literature.Methods: The clinical characteristics and response to rhGH treatment in 10 patients with GH1, GHR</...