hrp0082p2-d3-495 | Endocrine Oncology | ESPE2014

Early Occurrence of Graves’ Disease After Severe Hypothyroidism in Boy Irradiated for Hodgkin’s Disease

Cantelmi Grazia , Grandone Anna , Luongo Caterina , Affinita Maria Carmela , Micillo Flora , Ficociello Carmine , Indolfi Paolo , Casale Fiorina , Miraglia del Giudice Emanuele , Perrone Laura

Background: Thyroid dysfunction is a well-known endocrine complication after cervical irradiation for Hodgkin’s lymphoma (HL). The most common are primary hypothyroidism (20–30%), central hypothyroidism, transient thyroiditis and thyroid cancer. Graves’ disease (GD) is less frequent (5%).Objective and hypotheses: We describe a boy, already diagnosed with thyroiditis, who developed GD during follow-up for severe hypothyroidism following rad...