hrp0094p2-7 | Adrenals and HPA Axis | ESPE2021
van’t Westeinde Annelies
, Zimmermann Marius
, Savic Ivanka
, Lajic Svetlana
,
Objective: Oral hydrocortisone medication for Congenital Adrenal Hyperplasia (CAH) could lead to suboptimal blood cortisol levels throughout the day. In addition, the HPA-axis is rendered inflexible in patients. Cortisol is crucially involved in the stress response as well as in generating and regulating emotional responses to stimuli. Sub-optimal cortisol levels, in combination with a less flexible HPA-axis, could therefore lead to problems with emotion regul...