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hrp0098fc1.2 | Diabetes and Insulin | ESPE2024

Effect of hydroxychloroquine therapy in newly diagnosed type 1 diabetes: a randomised, double-blind, placebo-control pilot trial

George Arun , Kumar Rakesh , Patil Amol , Sachdeva Naresh , Yadav Jaivinder , Jacob Neenu , Banerjee Sayan , Nanda Pamali , Bala Anju

Background: Hydroxychloroquine sulfate (HCQS) is an immunomodulatory drug used to treat various rheumatological conditions. However, its effect on preserving β-cell function in type 1 diabetes remains unclear.Objective: To determine the differences in C-peptide (fasting and post mixed meal) and HbA1c in children with new-onset T1D on hydroxychloroquine therapy versus placebo.Methods:</...

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hrp0098p1-127 | Diabetes and Insulin 3 | ESPE2024

Molecular Characterization, Clinical phenotype and Long-Term Outcomes in Neonatal Diabetes Mellitus: nearly two decades of experience in a tertiary care pediatric diabetes clinic in north India

Kumar Rakesh , Dayal Devi , George Arun , Banerjee Sayan , Yadav Jaivinder , Bala Anju , Nanda Pamali , Evans Molly , Mohan Vishwanathan , Venkateshan Radha

Background: Neonatal diabetes mellitus (NDM) is a rare monogenic disorder that typically occurs within the first 6 months of life. However, there is limited information from India about the clinical characteristics, treatment, and long-term outcomes for children with NDM. This study aims to provide a comprehensive overview of one of India's largest cohorts of children with NDM. These children were treated at a single referral center in North India over a ...

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ESPE Abstracts

Effect of hydroxychloroquine therapy in newly diagnosed type 1 diabetes: a randomised, double-blind, placebo-control pilot trial

Molecular Characterization, Clinical phenotype and Long-Term Outcomes in Neonatal Diabetes Mellitus: nearly two decades of experience in a tertiary care pediatric diabetes clinic in north India

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