hrp0089p1-p172 | Growth & Syndromes P1 | ESPE2018

Early Gut Microbiota and childhood Growth

Schei Kasper , Salamati Saideh , Juliusson Petur Benedikt , Oien Torbjorn , Rudi Knut , Odegard Ronnaug Astri

Introduction: Physical growth according to genetic potential is a hallmark of childhood health [1]. Childhood growth is complex and the physiological processes involved in promoting healthy growth are not fully understood, including the gut microbiota. The gut microbiota matures from birth towards adulthood, and this process might be affected by several factors, including mode of delivery, food intake and antibiotic treatment. The bacterial gut microbiota is observed to be mor...

hrp0089p1-p212 | Pituitary, Neuroendocrinology and Puberty P1 | ESPE2018

Real-World Safety Data in a Cohort of Children with Noonan Syndrome Treated with GH: Final Results from NordiNet International Outcome Study (IOS) and ANSWER Program

Juliusson Petur Benedikt , Dahlgren Jovanna , Abuzzahab M Jennifer , Pedersen Birgitte Tonnes , Roehrich Sebastian , Romano Alicia

Objectives: Current safety data do not indicate an association of GH therapy with increased risk for development/progression of tumours, or worsening of congenital cardiac conditions in individuals with Noonan syndrome (NS); however, data are limited. This report describes real-world safety data on GH therapy in paediatric patients with NS.Methods: Two complementary non-interventional, multicentre studies, NordiNet IOS (NCT00960128) and ANSWER Program (N...

hrp0082p2-d2-464 | Growth (1) | ESPE2014

Interrelationships Between BMI and Other Overweight Related Anthropometric Variables in Childhood

Brannsether Bente , Eide Geir Egil , Roelants Mathieu , Bjerknes Robert , Juliusson Petur Benedikt

Background: Anthropometry is the general tool for defining overweight and obesity, with BMI cut-offs adjusted for sex and age, as the most commonly used variable in childhood.Objective and hypotheses: Based on the interrelationships between BMI and different overweight-related anthropometric variables we wanted to find out which anthropometric variables contribute most to the variation in BMI, and how age affect this picture?Method...