hrp0092p3-206 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

Unusual Cause of Hypopituitarism: A Niemann Pick Disease

Safi Wajdi , Kacem Faten Hadj , Naifar Manel , Kallel Faten , Ayadi Fatma , Feki Mouna Mnif , Abid Mohamed

Introduction: Niemann Pick type B (NMP B) is a rare lysosomal storage disease caused by mutations in the SMPD1 gene. Typically, had normal height and weight. In this work, we report an unusual association of a Niemann Pick disease in a child with hypopituitarism.Case:We report the case of a young boy who was hospitalized at the age of 11, in Hematological Department for splenomegaly and polyadenopathies where the d...