hrp0082p2-d3-559 | Puberty and Neuroendocrinology (2) | ESPE2014

The Buserelin Stimulation Test Given as an Intranasal Spray in Diagnosing Gonadotropin Deficiency in Males with Delayed Puberty

Rakhimova Gulnara , Gilyazetdinov Kamil

Background: Because of episodic secretion of gonadotropins (LH, and FSH), basal levels of these hormones can not objectively be assessed to differentiate delayed puberty in males.Objective and hypotheses: To assess the efficacy of the GnRH agonist (as spray) in diagnosing of delayed puberty in males.Method: Prepubertal males (n=18; age range 13.3–18.5 years) were studied; buserelin 0.15 (spray) μg was administere...

hrp0084p3-926 | GH & IGF | ESPE2015

Usefulness of Priming with Gonadal Steroids Prior to GH Stimulation with Clonidine in the Evaluation of the GH Status of Short Children

Rakhimova Gulnara , Gilyazetdinov Kamil

Aim: To determine the usefulness of priming with gonadal steroids prior to GH stimulation with clonidine in the evaluation of the GH status of short children.Method: 21 males were studied, with a mean chronological age of 13.2±1.5 years (range 11–16 years), mean bone age 11.0±1.4 years, Tanner stage 1–2, with height 135.8±7.4 cm (Ht-SDS −2.8±0.5), and an inadequate response to an initial GH stimulation test with clonid...

hrp0094p2-336 | Multisystem endocrine disorders | ESPE2021

Endocrine and metabolic complications according to genotype in Prader-Willi syndrome

Young Yoon Ju , Dong Yoo Suk , Abdumonnanovich Mamatkulov Elbek , Nailevich Gilyazetdinov Kamil , Cheon Chong Kun ,

Objective: Prader-Willi syndrome (PWS) is a complex genetic disease associated with hypothalamic-pituitary dysfunction, severe obesity and metabolic dysfunctions. The aim of this study was to describe endocrine and metabolic profiles in PWS children and young adults.We also investigated the differences in clinical outcomes according to genotype.Methods: Data of 64 children and adults with genetically verified PWS aged mo...