hrp0089p1-p023 | Adrenals and HPA Axis P1 | ESPE2018

Associations Between Maternal and Offspring Hair Cortisol Concentrations and Child Behavioral Symptoms in Pairs of Children 18–48 Months Old and their Mothers With and Without Perinatal Mental Disorders

Agapaki Anna , Papagianni Fenia , Valavani Eleni , Zervas Ioannis , Mantziou Aimilia , Kanelli Stamatina , Spyropoulou Areti , Chrousos George , Pervanidou Panagiota

Introduction: Maternal perinatal mental disorders (PMDs) are associated with developmental and behavioral problems in the offspring, probably mediated by the programming of the limbic-hypothalamic-pituitary-adrenal (LHPA) axis. Increased or decreased cortisol concentrations during pregnancy and the perinatal period have been associated with alterations in the stress responses of the offspring and with child behavioral problems; however, such associations remain unclear.<p ...