hrp0095p2-93 | Fat, Metabolism and Obesity | ESPE2022

The Relationship Between Serum AMH Levels and Puberty in Obese Girls

Sarikaya Emre , Cicek Dilek , Gok Ebru , Kara Leyla , Gul Siraz Ulku , Hatipoglu Nihal

Objectives: Anti-Müllerian hormone (AMH) is produced by Sertoli cells in the testicles and granulosa cells in the ovaries. Increased abdominal adipose tissue initiates metabolic and endocrine disorders and predisposes to polycystic ovary syndrome. AMH is used as a marker in PCOS. A decrease in AMH levels has been reported in adults with obesity and increased central adiposity. The purpose of this study was to assess the serum AMH level and related factors...

hrp0095p2-168 | Growth and Syndromes | ESPE2022

Two siblings whose differential diagnosis with rickets; Schmid Metaphyseal Chondrodysplasia

Sarikaya Emre , Gok Ebru , Kara Leyla , Berber Mg ur , Gul Siraz Ulku , Hatipoglu Nihal

Entry: Rickets is a generalized metabolic bone disease manifested by the abnormal increase in osteoid tissue, defective mineralization and deformation of the epiphyseal plate, which occurs as a result of vitamin D and mineral deficiency before epiphysial fusion occurs in adolescence. Although rickets is mostly seen due to vitamin D deficiency, it can rarely be seen in vitamin D metabolism disorders and diseases that cause phosphorus loss. Clinical findings suc...

hrp0095p1-332 | Growth and Syndromes | ESPE2022

Growth Hormone Therapy Experience in a Patient with Hypotonia Cystinuria Syndrome

Sarıkaya Emre , Berber Uğur , Gök Ebru , Kara Leyla , Gül Şiraz Ülkü , Hatipoğlu Nihal

Background: Hypotonia-Cystinuria Syndrome (HCS) is a rare autosomal recessive disease characterized by generalized hypotonia, nephrolithiasis, short stature, minor facial dysmorphism, hyperphagia, and rapid weight gain in late childhood. Microdeletion can be detected in part of the SLC3A1 and PREPL genes in these cases. Growth hormone deficiency is rarely seen in these patients and adequate growth can be achieved with growth hormone therapy.<p class="abste...

hrp0095p2-208 | Multisystem Endocrine Disorders | ESPE2022

Precocious puberty before and after the COVID-19 pandemic

Gök Ebru , Sarıkaya Emre , Kara Leyla , Berber Uğur , Gül Şiraz Ülkü , Hatipoğlu Nihal

Introduction: A novel coronavirus defined as coronavirus disease 2019 (COVID-19) was first detected in China at the end of 2019 and spread rapidly all over the world. As the covid 19 pandemic has led to changes in life all over the world, the prognosis of diseases have also been affected. This study presents how early puberty has been affected during the pandemic period.Method: A total of 210 subjects; 113 individuals (9...

hrp0095p1-198 | Thyroid | ESPE2022

FT3:FT4 ratio be used to predict relapse and remission? Single Centre Experience

Kara Leyla , Çiçek Dilek , Sarıkaya Emre , Gök Ebru , Berber Uğur , Gül Şiraz Ülkü , Kurtoğlu Selim , Kendirci Mustafa , Hatipoğlu Nihal

Introduction: Graves’ Disease (GD) is autoimmune hyperthyroidism occurring mostly in adolescent girls. The main pathogenic role of the disease is attributed to TSH receptor antibodies (TRAb), which stimulate the thyroid gland to increase the production of the most active thyroid hormone- triiodothyronine (T3). High levels of TRAb and a large goitre size are commonly known as poor prognostic factors for the disease and are used to predict relapse.<p c...

hrp0095p1-600 | Thyroid | ESPE2022

Response to Growth Hormone Therapy in Turner And Noonan Syndrome: First Year And Final Height

Kara Leyla , Çiçek Dilek , Sarıkaya Emre , Gök Ebru , Berber Uğur , Gül Şiraz Ülkü , Kurtoğlu Selim , Kendirci Mustafa , Hatipoğlu Nihal

Background: Despite different genetic backgrounds, Noonan syndrome (NS) shares similar phenotype features to Turner syndromes (TS) such as short stature, webbed neck and congenital heart defects. The primary cause of short stature in Turner syndrome and Noonan syndrome is GH resistance [1]. Recombinant human growth hormone (rhGH) is being used to promote linear growth in short children with Noonan syndrome. However, its efficacy is still controversial.<p c...