hrp0086p2-p791 | Pituitary and Neuroendocrinology P2 | ESPE2016

Menstrualcharacteristics and Problems in 9–18 Years Old Turkish School Girls

Kendirci Mustafa , Yucel Gul , Gul Ulku

Background: The aim of this study is to determine menstruating girls’ sectional characteristics and the frequency of the menstrual problems.Method: The study was done in randomly selected primary, junior and high schools at Kayseri Province between December 2014–March 2015. After obtaining the permits adolescent girls in 9–18 age groups were included in the study. Following preliminary information, informed consent forms and questionnaires...

hrp0092p1-244 | Multisystem Endocrine Disorders | ESPE2019

Two Different Endocrine Cancer, One Disease; DICER-1 Mutation

Tatli Zeynep Uzan , Direk Gül , Özcan Alper , Hatipoglu Nihal , Kendirci Mustafa , Kurtoglu Selim

Autosomal dominant DICER1 mutations are among the causes of early-onset familial cancer. DICER1 mutation has been shown in pleuropulmonary blastomas as well as ovarian tumors, thyroid, parathyroid, pituitary, adrenocortical and testicular tumors. It is important to be aware of the risk for the development of other cancers in the follow-up of these cases.Cases: Case-1: Previously known to be healthy 8,5-year-old girl presented with compla...

hrp0086p2-p55 | Adrenal P2 | ESPE2016

The Treatment of a Functional Adrenocortical Cancer with Mitotane

Kurtoglu Selim , Hatipoglu Nihal , Gul Ulku , Tatlı Zeynep Uzan , Akın Leyla , Kendirci Mustafa

Introduction: In the pediatric age group, the incidence of the adrenocortical cancer (ACC) is 0.2%. The effective treatment is surgical resection. The only medical option is mitotane but it has negative effects on steroidogenesis. The difficulty in the management of mitotane therapy is discussed in this case.Case report: An 1110/12 years-old boy was referred with A 5 cm diameter solid-hypoecoic mass observed by sonography in the left surrenal ...

hrp0086p2-p783 | Pituitary and Neuroendocrinology P2 | ESPE2016

Basal Levels of FSH and LH can be Helpfull in Diagnosis of Puberty Precocious?

Gul Ulku , Samur Bahadir , Tatlı Zeynep Uzan , Hatipoglu Nihal , Kendirci Mustafa , Kurtoglu Selim

Background: Luteinizing hormone stimulating hormone (LHRH) test is the gold standard test in the diagnosis of puberty precocıous (PP). The basal levels of FSH (follicular stimulating hormone) and LH (luteinizing hormone) cannot be always reliable.Objective and hypotheses: To investigate the relation between the LHRH test and basal levels of FSH and LH.Method: Girls with puberty started before the age 8 are investigated. Eighty...

hrp0082p3-d2-745 | Diabetes (3) | ESPE2014

A Case of Type 2 Diabetes Associated with Ichthyosis: Chanarin–Dorfman Syndrome

Hatipoglu Nihal , Okdemir Deniz , Akin Leyla , Gokay Songul , Kardas Fatih , Kendirci Mustafa , Gul Ulku , Kurtoglu Selim

Background: Chanarin–Dorfman syndrome is a rare autosomal recessively inherited neutral lipid disorder which is characterized by congenital ichthyosis and multiple system involvement. It is diagnosed by visualization of lipid vacuoles in neutrophiles (Jordon anomaly) in suspicious cases. This syndrome can be associated with type 2 diabetes.Aim: We wished to remind this very rare disease in differential diagnosis of ichthyosis associating with diabet...

hrp0082p3-d3-750 | Diabetes (4) | ESPE2014

A Case of Type 1 Diabetes Associated with Cerebellar Ataxia: Stiff-Person Syndrome

Kurtoglu Selim , Okdemir Deniz , Hatipoglu Nihal , Akin Leyla , Gul Ulku , Canpolat Mehmet , Kendirci Mustafa

Background: Stiff-person syndrome (SPS) is a rare disorder which is characterized by muscle rigidity, spasm and cerebellar abnormalities. The etiology is not clarified yet. 80% of cases are caused by an autoantibody against GAD that inhibits synthesis of GABA. Other autoimmune diseases such as type 1 diabetes mellitus and thyroiditis are often associated.Aim: To underline the importance of considering SPS in differential diagnosis of patients with type 1...

hrp0084p2-576 | Thyroid | ESPE2015

Relationship between Cord Blood Phthalates and Maternal and Neonatal Thyroid Functions

Ozsoylu Serkan , Akin Leyla , Gunes Tamer , Kendirci Mustafa , Narin Figen , Kurtoglu Selim

Background: Phthalates are industrial chemicals extensively used as plasticizers in a variety of commercial products. Di-(2-ethylhexyl) phthalate (DEHP) is one of the most frequently used phthalates. DEHP is readily metabolized to mono-(2-ethylhexyl) phthalate (MEHP), which is more toxic than its parent compound. There are some animal and in vitro studies suggesting that phthalates can disrupt hypothalamus-pituitary-thyroid axis.Objective and hy...

hrp0084p3-620 | Adrenals | ESPE2015

A Rare Cause of Hypertensıon: Pseudophaeochromocytoma

Hatipoglu Nihal , Gul Ulku , Okdemir Deniz , Akin Leyla , Kendirci Mustafa , Kurtoglu Selim

Background: Although phaeochromocytoma is commonly considered in the differential diagnosis paroxysmal hypertension, only a small percentage of patients are actually diagnosed with this disorder. After exclusion of phaeochromocytoma, panic attack and pseudophaeochromocytoma should be considered in the differential diagnosis in patients with these symptoms. Here we report a rare case of pseudophaeochromocytoma presented with severe symptomatic hypertension attacks.<p class=...

hrp0084p3-666 | Bone | ESPE2015

Parathyroid Adenoma Should be Considered in the Management of Hypophosphataemic Rickets

Okdemir Deniz , Gul Ulku , Akin Leyla , Hatipoglu Nihal , Kendirci Mustafa , Kurtoglu Selim

Background: X-linked dominant hypophosphatemic rickets (XLHR) is a rare hereditary metabolic bone disorder. Calcitriol and phosphates are used for the treatment and hyperparathyroidism rarely occurs as a complication. We report a case of XLHR who developed autonomous parathyroid hyperfunction during treatment and underwent surgery for that.Case: A male patient was presented with short stature and bone deformities at age 11 months and diagnosed with XLHR ...

hrp0084p3-803 | DSD | ESPE2015

A Case of Klinefelter Syndrome with an Atypical Presentation

Gul Ulku , Bas Veysel Nijat , Okdemir Deniz , Akin Leyla , Hatipoglu Nihal , Kendirci Mustafa , Kurtoglu Selim

Background: Klinefelter syndrome, also known as 47, XXY, is a disorder characterized by tall stature, hypogonadism and mental retardation which is caused by nondisjunction events during meiosis and occurs in 500–1 000 live male birth. Here we report a patient with Klinefelter syndrome who presented with short stature, in contrast to common tall stature presentation and was diagnosed with GH deficiency.Case: A 7-year-old male presented with short sta...