hrp0098p2-9 | Adrenals and HPA Axis | ESPE2024

The Role of Midkin and Inflammatory Cytokines in The Pathophysiology of Metabolic Syndrome in Children and Adolescents with Classical Congenital Adrenal Hyperplasia Due to 21 Hydroxylase Enzyme Deficiency.

Çetinkaya Semra , Kesikli Burcu , Ayral Arıbal Pelin , Yazıhan Nuray

Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase(21-OH) deficiency is the most common type of CAH. In the treatment, the insufficinet hormones are replaced. The excess doses cause hypercortisolism, insufficient doses; causes hyperandrogenism. Both metabolic conditions; It has been found to be associated with comorbidities that increase the risk of cardiovascular disease. Here, it is aimed to determine the comorbidities that increase the risk of cardiovascular disease...