ESPE Abstracts

Context: Acute or chronic metabolic derangement after solid organ transplantation (SOT) can result in endocrine complications. As survival rates following SOT have significantly increased, the occurrence of endocrine complications has also risen.Objective: This study was performed to investigate long-term endocrine complications after SOT in children and adolescents.Methods: This s...

Background: Isolated gonadotropin-releasing hormone deficiency (IGD) is a genetically heterogeneous disorder caused by >60 genes resulting in a broad range of clinical manifestations and classified into Kallmann syndrome (KS) with anosmia and normosmic isolated hypogonadotropic hypogonadism (nIHH). Despite the advent of next-generation sequencing technology, ~50% of the cases remain genetically undiagnosed. Previously, copy number variations (CNVs) in known...