hrp0092p1-60 | Fat, Metabolism and Obesity | ESPE2019

The Effect of Improved Metabolic Risk Factors and Metformin Therapy on Circulating Hepatokines in Obese, Insulin-Resistant Adolescents

Kilinç Suna , Kirankaya Aysegül , Atay Zeynep

Introduction: The molecular mechanisms underlying insulin resistance (IR) is complex and has not been fully elucidated yet. The experimental studies point out the role of liver-derived proteins, called hepatokines.Aims: To compare metabolic parameters and hepatokines levels in obese adolescents and healthy controls and to assess the effect of metformin therapy on plasma hepatokines levels in obese, insulin-resistant adol...

hrp0092p1-294 | Thyroid (1) | ESPE2019

Effect of serum TSH level on ovarian volume in prepubertal girls with subclinical hypothyroidism

Yigit Özgül , Sert Tugba , Ekinci Deniz , Kirankaya Aysegül , Kilinç Suna

Background and Objectives: Enlargement and cystic changes in ovaries of patients with longstanding overt hypothyroidism has been observed in numerous case reports. But there is limited data about the effect of subclinical hypothyroidism (SH) on ovarian volume and ovarian cyst formation. We evaluated the relationship between serum thyroid stimulating hormone (TSH) level and ovarian volume and sonographic appearance in prepubertal girls with SH.<p class="abs...