ESPE Abstracts

ESPE Abstracts

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hrp0095p1-172 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Diabetes type 1 can induce testicular atrophy with Leydig cell hyperplasia and germ cell depletion and therefore prevents reproductive function and fertility in rats

Viola Wagner Isabel , Kloeting Nora , Kulle Alexandra , Rieck Karen , Söder Olle , Hiort Olaf

Research Aim: Diabetes type 1 can negatively influence testicular function and fertility but the pathomechanisms on the testicular level remain to be elucidated. Therefore, the aim of the study was to evaluate effects of diabetes mellitus type 1 disease on testicular function.Material and Methods: BB/OKL rats developed type 1 diabetes during adolescence. Rats were treated with different Insulin implants to achieve suffic...
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ESPE Abstracts

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