hrp0089p2-p037 | Bone, Growth Plate & Mineral Metabolism P2 | ESPE2018

Vitamin D Deficient (Nutritional) Rickets Presenting in Infancy

Prematilake Dilusha , Hashim Raihana , Kollurage Udeni , Atapattu Navoda

Background: Nutritional rickets is a disorder of defective chondrocyte differentiation and mineralization of the growth plate and osteoid due to vitamin D deficiency with or without low calcium intake in growing children. Maternal Vitamin D deficiency and exclusive breastfeeding without supplementation are the most frequent causes of rickets in the infancy. Vitamin D deficiency is still a problem in Sri Lanka in spite of sun shine throughout the year. We present a case series ...

hrp0097p2-245 | Late Breaking | ESPE2023

Neonatal Hypocalcaemia and association with maternal Magnesium sulphate (MgSO4) administration in a single center neonatal unit

Kollurage Udeni , Morley Elizabeth , Baachaa Zuro , Dogar Azeem , Gireesh Rayasandra

Introduction: Hypocalcaemia is a biochemical abnormality noted in neonates and considered a possible side effect of maternal MgSO4 administration. Suggested mechanism is MgSO4 treatment increase maternal hypermagnesemia, inhibiting maternal parathyroid hormone secretion leading to maternal and foetal/neonatal hypocalcaemia.Objectives: This study is aimed to identify common risk factors, presentation, biochemical abnormal...

hrp0092p2-80 | Diabetes and Insulin | ESPE2019

Effect of Multiple dose Insulin on Glycaemic Control and Adiposity in Children and Adolescents with Type 1 Diabetes; a Sri Lankan Experience

Hashim Raihana , Hoole Thabitha , Prematilake Dilusha , Kollurage Udeni , Gunasekara Buddi , Suntharesan Janani , Atapattu Navoda

Objective: To describe the glycaemic control and change in body mass index (BMI) in children and adolescents with type 1 diabetes (T1DM) after converting to multiple dose insulin regime (MDI) from fixed dose insulin regime (FD).Methods: A retrospective observational study on children with T1DM who were converted to MDI from FD at the Lady Ridgeway Hospital from January 2013 to June 2018. Mean haemoglobin A1c(H...

hrp0089p3-p058 | Bone, Growth Plate & Mineral Metabolism P3 | ESPE2018

Severe Neonatal Hypercalcemia: A Challenging Case

Hashim Raihana , Prematilake Dilusha , Gunasekara Buddi , Suntharesan Jananie , Kollurage Udeni , Atapattu Navoda

Neonatal severe hyperparathyroidism (NSHPT) is a rare autosomal recessive disorder due to inactivating mutations of calcium-sensing receptor. These receptors are vital in calcium homeostasis and are expressed in a number of tissues such as parathyroid glands, renal tubules and bone. Homozygous mutations lead to severe hypercalcemia and life-threatening bone demineralization if untreated. A neonate born to 2nd degree consanguineous parents presented with poor feeding...

hrp0089p3-p227 | Growth & Syndromes P3 | ESPE2018

Auditing Presentation, Investigations and Management of Turner’s Syndrome

Gunasekara Buddhi , Premathilaka Dilusha , Hasheem Raihana , Kollurage Udeni , Suntharesan Janani , Jeyanthakumar Rasarathinum , Armugam Puvana , Atapattu Navoda

Background: Turner’s syndrome (TS) is the most common genetic disorder in females affecting approximately 1 in 2500 live female births as a result of partial or complete X chromosomal monosomy. TS mostly affect skeletal, cardiovascular, endocrine and reproductive systems. Girls with TS present with short stature and dysmorphic features such as webbed neck and delayed puberty. Age at diagnosis of children with TS is extremely important to start growth hormone at younger ag...