ESPE Abstracts

Introduction: Mini-puberty is defined as the transient activation of the hypothalamic-pituitary-gonadal (HPG) axis during the first 3-6 months of life. Postnatal HPG activation occurs more robustly and for a longer duration in premature infants compared to term infants. In this report, we present a case of severely premature infant who presented with vaginal bleeding during the mini-puberty period.Case: A 5-month and 12-...

Introduction: Adipsic diabetes insipidus (ADI) arises from the destruction of both antidiuretic hormone (ADH) neurons and osmoreceptors in the hypothalamus. This condition is characterized by polyuria, loss of thirst sensation and hypernatremia. Managing serum sodium levels is particularly challenging, often resulting in fluctuations in serum sodium and osmolality, which elevate the risk of morbidity and mortality. This report presents the clinical follow-up o...

Introduction: Neonatal diabetes mellitus (NDM) is a rare monogenic disease associated with genetic defects in pancreatic beta cell number and/or function. It can be divided into two forms: transient neonatal diabetes mellitus (TNDM) and permanent neonatal diabetes mellitus (PNDM). TNDM is usually diagnosed within the first month after birth and usually regresses before the age of one year, but may reappear during adolescence. In contrast, PNDM is a lifelong di...