ESPE Abstracts

ESPE Abstracts

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hrp0092p2-229 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

Normalized Pubertal Tempo of Masculinisation and Pubertal Height Gain in Boys With MPHD, Using a Physiological Treatment Approach with Low Dose Testosterone and Adequate Dose rhGH

Lundberg Elena , Kriström Berit , Albertsson-Wikland Kerstin

Background: Masculinisation tempo on sex-steroid replacement in boys with multiple pituitary hormone deficiencies (MPHD) and pubertal growth spurts on adequate GH-treatment regimens were unknown in 1989 and are still not optimal.Objective and Hypotheses: A hypothesis driven prototype trial1,2 was initiated in the late 80ies aiming to mimic normal puberty3 regarding both degree and tempo of masculini...
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hrp0092p2-220 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

Normalized Pubertal Tempo of Maturation and Pubertal Height Gain in Girls with MPHD, Using a Physiological Treatment Approach with Natural Estrogens & rhGH

Lundberg Elena , Kriström Berit , Holmlund Mariell , Albertsson-Wikland Kerstin

Background: Pubertal tempo of breast development on natural sex-steroid replacement therapy in girls with multiple pituitary hormone deficiencies (MPHD) and pubertal growth spurts on adequate GH-treatment regimens were unknown in 1989 and are still not known.Objective and Hypotheses: A hypothesis driven prototype trial1,2 was initiated in the late 80ies aiming to mimic normal puberty regarding both pubertal ma...
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hrp0092p1-227 | Growth and Syndromes (to include Turner Syndrome) (1) | ESPE2019

Latest Results From PATRO Children, a Multi-Centre, Observational Study of the Long-Term Safety and Effectiveness of Omnitrope® in Children Requiring Growth Hormone Treatment

Kanumakala Shankar , Pfäffle Roland , Höybye Charlotte , Kriström Berit , Battelino Tadej , Zabransky Markus , Zouater Hichem

Objectives: PATRO Children is an observational, international, longitudinal study of the long-term safety of a recombinant human growth hormone (rhGH; Omnitrope®, Sandoz). In particular, the study will assess the impact of rhGH on glucose metabolism and risk of malignancies. Long-term effectiveness is a secondary objective.Methods: The study population includes infants, children and adolescents receiving ...
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ESPE Abstracts

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