hrp0098p2-26 | Bone, Growth Plate and Mineral Metabolism | ESPE2024

Bisphosphonate Therapy in a Pediatric Case Series with Monostotic Form of Fibrous Dysplasia: A Single-Center Retrospective Analysis of Efficacy and Safety

Ilic Nikola , Cvetkovic Dimitrije , Paunovic Zoran , Bogosavljevic Marko , Krstic Jovana , Todorovic Sladjana , Sarajlija Adrijan

Background: Fibrous dysplasia (FD) is a rare bone disorder characterized by the proliferation of fibrous tissue within the bone, leading to pain, deformity, and an increased fracture risk. While management primarily focuses on symptomatic relief, surgical interventions, calcium supplementation, and vitamin D therapy, bisphosphonates have been used as a therapeutic option in children. However, studies of bisphosphonate efficiency have shown inconclusive results...