hrp0092p2-184 | Growth and Syndromes (to include Turner Syndrome) | ESPE2019

Effect of Gonadotropin-Releasing Hormone Agonists on Auxological Outcomes of Korean Boys with Central Precocious Puberty and Early Puberty

Lee Hae Sang , Sohn Young Bae , Kum Chang Dae , Hwang Jin Soon , Lim Jung Sub

Objective: To determine the effect of gonadotropin-releasing hormone agonist (GnRHa) treatment on auxological outcome of Korean boys with central precocious puberty (CPP) and early puberty (EP).Methods: This study included 11 boys with CPP and 8 boys with EP who were treated with GnRHa for at least 2 years at the Pediatric Endocrine Unit of Ajou University Hospital from March 2003 to December 2015. All nineteen boys atta...

hrp0092p1-138 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Changes in Body Mass Index in Boys with Central Precocious Puberty During and After Gonadotropin-Releasing Hormone Agonist Treatment

Kum Chang Dae , Rho Jung Gi , Lim Kyung In , Lim Jung Sub , Lee Hae Sang , Hwang Jin Soon

Background: Gonadotropin-releasing hormone agonist (GnRHa) treatment is widely used for central precocious puberty (CPP). Although some authors found increases in body mass index (BMI) in girls after GnRHa treatment, most studies reported no significant difference in BMI in girls during and after treatment. However, few studies have investigated changes in BMI in boys with CPP during and after GnRHa treatment. Hence, we aimed to evaluate the effects of GnRHa t...