hrp0098p2-377 | Late Breaking | ESPE2024

The etiology of Central Precocious Puberty and the Impact of Gonadotropin-Releasing Hormone Agonist Therapy: Albanian experience.

Gjikopulli Agim , Tomori Sonila , Kollcaku Laurant , Kurti Era , Velija Liljana , Cullufi Paskal

Introduction: Central precocious puberty (CPP) occurs when the HPG axis is activated prematurely. As a result, the affected child develops secondary sexual characteristics earlier than is typical for the average pediatric population. The child experiences accelerated bone maturation and premature closure of the epiphyseal growth plates, resulting in reduced adult stature. The mainstay of CPP treatment is a gonadotropin-releasing hormone analog (GnRHa) that sup...