hrp0098p3-320 | Late Breaking | ESPE2024

Predictive factors of persistent gh deficiency and impact on the final height: a retrospective cohort study

Urbano Flavia , Chiarito Mariangela , Antonio Moscogiuri Luigi , Lattanzio Crescenza , Valerio Giannico Orazio , Annesi Gabriele , Zecchino Clara , Maria Felicia Faienza

Introduction: Most children with isolated GH deficiency (GHD) show a normal GH secretion upon reaching final height (FH). The aimof our study was to identify the predictive factors of persistent GHD and the correlation with the response to recombinant GH (rhGH) therapy in terms of height gain upon reaching FH and compared to target height (TH).Method: In this retrospective study, we evaluated medical records of GHD subje...

hrp0097p1-404 | Adrenals and HPA Axis | ESPE2023

Nephrocalcinosis: an emerging issue in children with Congenital Adrenal Hyperplasia

Chiarito Mariangela , Lattanzio Crescenza , D'Ascanio Vito , Capalbo Donatella , Cavarzere Paolo , Grandone Anna , Luongo Caterina , Pepe Giorgia , Wasniewska Malgorzata , Zoller Thomas , Salerno Mariacarolina , Felicia Faienza Maria

Hypercalcemia and nephrocalcinosis (NC) are rare findings associated with congenital adrenal hyperplasia (CAH), whose pathogenetic mechanisms are still unclear. In this study we aimed to investigate the prevalence of NC in a cohort of Italian children affected with classical form of CAH, and to correlate its association with metabolic control of the disease.Subjects and Methods: This is a multicenter one year-perspective study involving ...