hrp0095p1-239 | Diabetes and Insulin | ESPE2022

Why understanding hemoglobin glycated measurement can be important: Santa Juana hemoglobin variant and falsely elevated HbA1c

Lorand Juan , Boutsen Laure , Gueulette Emmanuelle , Maisin Diane , Closset Mélanie , Mouraux Thierry , Beckers Dominique

Diabetes mellitus is a chronic disease. The risk of microvascular complications is correlated with hemoglobin A1c (HbA1c) level [1] Educating the diabetic patient to keep an HbA1c below 7% reduce the risk of long-term complications. We report the case of a 15 years old teenager, with chronical headache, referred for diabetes mellitus with a fasting glycemia of 83 mg/dl (normal < 100) and an HbA1C of 8.3% using an Ion-exchange High Performance Liquid Chromatography (HPLC, Ad...

hrp0098p2-173 | Growth and Syndromes | ESPE2024

Prevalence and changes in genetic and clinical abnormalities in growth hormone-treated girls with Turner syndrome: a study from the Belgian-Luxembourgish growth hormone registry (BELGROW)

Boutsen Laure , Thomas Muriel , De Schepper Jean , Verlinde Fransiska , Beckers Dominique , Heinrichs Claudine , Casteels Kristina , Cools Martine , Dotremont Hilde , Brachet Cécile , Parent Anne-Simone , Lambert Sophie , Massa Guy , Klink Daniel , Logghe Karl , Depoorter Sylvia , Fudvoye Julie , Reynaert Nele , Becker Marianne , Lysy Philippe

Background: Since the initial clinical description of Turner Syndrome (TS), there have been notable changes in the genotypic and phenotypic presentation of the disease. Our aimis to provide an overview of the current genetic and clinical characteristics of a large Belgian cohort of girls with TS, and the evolution over the last 3 decades.Methods: We therefore analyzed the genetic and clinical data of growth hormone(GH)-t...