hrp0084p3-942 | GH & IGF | ESPE2015
van der Steen Manouk
, Lem Annemieke J
, van der Kaay Danielle C M
, Hokken-Koelega Anita C S
Background: Pubertal children born small for gestational age (SGA) with a poor adult height (AH) expectation can benefit from treatment with GH 1 mg/m2 per day (~0.033 mg/kg per day) in combination with 2 years of GnRH analogue (2 years GnRHa) and even more so with 2 mg/m2 per day (~0.067 mg/kg per day). Concerns haven been raised about the effects of GH and GnRHa on insulin sensitivity on the long-term.Objective and hypotheses: To ...