hrp0095p1-45 | Diabetes and Insulin | ESPE2022

Non-insulin-dependent diabetes mellitus due to a variant in MAPK8IP1: a case report

Angulo-Mosquera Mario , Aguirre Marisol , Pachajoa Harry , Lemus Rodrigo , Mejia-Zapata Liliana , Larrañaga Isabella

Introduction: non-insulin-dependent diabetes mellitus (type II) is an increasing problem in childhood. With the advancement of genetic testing and genome-wide association studies, mutations in genes causing loss or dysfunction of the pancreatic cell have been associated with type II diabetes. A heterozygous mutation of the MAPK8IP1 (Mitogen-activated protein kinase 8 interacting protein 1) gene is associated with a rare form of diabetes with few cases reported...