hrp0098p2-148 | GH and IGFs | ESPE2024

The Diagnostic Effectiveness of Low IGF-1 Combined with a Single Insulin Tolerance Test for the Diagnosis of Growth Hormone Deficiency

Lerdrassameethad Worapimon , Srilanchakon Khomsak

Introduction: Currently, there is no diagnostic gold standard for growth hormone deficiency (GHD). The diagnosis of GHD is based on the current consensus guidelines, which state that an inadequate GH level of 7 ng/mL during two growth hormone stimulation tests (GHSTs) is indicative of GHD. The primary objectives of this study were to assess the sensitivity and specificity of low IGF-1 levels in combination with a single insulin tolerance test (ITT) for diagnos...

hrp0098p1-115 | Bone, Growth Plate and Mineral Metabolism 2 | ESPE2024

Unusual Presentation of Tumor-Induced Osteomalacia with Suppressed FGF-23 in an 8-Year-Old Boy

Lerdrassameethad Worapimon , Promsod Ornpisa , Charoenlap Chris , Ariyachaipanich Aticha , Sahakitrungruang Taninee

Objectives: This report presents the unusual case of an 8-year-old boy with tumor-induced osteomalacia (TIO) characterized by suppressed FGF-23 levels.Case Presentation: An 8-year-old boy presented with a six-month history of left knee pain, exacerbated by walking. Physical examination revealed genu valgus without signs of inflammation. X-rays indicated rickets, prompting a referral to a pediatric endocrinology clinic. L...