hrp0086p1-p22 | Adrenal P1 | ESPE2016
, Lewis Sarah
, Coveney John
, Roche Edna F.
Background: In children with PraderWilli Syndrome (PWS), hypothalamic dysfunction plays a key role in the development of aberrant energy regulation, sleep-related breathing disorders, hypogonadism and impaired linear growth. Dysfunction of the hypothalamicpituitaryadrenal (HPA) axis may contribute to the high incidence of sudden death. The prevalence and the extent of the dysfunction of HPA axis remain unclear.Method: Thirty-one (10M/21...