hrp0098rfc4.1 | Adrenals and HPA Axis 1 | ESPE2024

Screening for Adrenal Insufficiency in Children by Home Waking Salivary Cortisone testing

Craig Jessica , Tavernier Mathilde , Ross Callum , Lewis Jen , Jacques Richard , Keevil Brian , Ross Richard , Debono Miguel , Elder Charlotte

Background: The current screening test for adrenal insufficiency (AI) involves patients traveling to attend hospital for an “early” morning serum cortisol (EMC) sample, generally taken some considerable time after the child has woken. This risks missing the morning cortisol peak, leading to false positive results and necessitating further testing, usually by the Short Synacthen Test (SST). Both EMC and SST require venepuncture, which is resource in...