hrp0098fc13.3 | Pituitary, Neuroendocrinology and Puberty 2 | ESPE2024

Effect of Precocious Puberty and GnRHa Treatment on Glucose Metabolism in Female Rats

Lin Xiaoya , Chen Qiuli

Objective: In order to investigate the effect of precocity and gonadotropin-releasing hormone analogists (GnRHa) GnRHa treatment on glucose metabolism in female rats, the possible mechanism was studied through the changes of leptin, estrogen, growth hormone, insulin-like growth factor 1 and insulin receptor signal crosslinking pathway.Methods: Forty-eight 2-day-old female Sprague-Dawley (SD) suckers were randomly divided...