hrp0095rfc4.5 | Fat, Metabolism and Obesity | ESPE2022
Elsworth Rebecca L.
, Naeem Nimra
, Hawton Katherine
, Narayan Kruthika
, Elson Ruth
, Taylor-Miller Tashunka
, Lithander Fiona E.
, Hamilton-Shield Julian P.
, Crowne Elizabeth C.
, Hinton Elanor C.
Background: Craniopharyngioma is a non-malignant embryonic tumour in the pituitary-hypothalamic area, associated with hypothalamic obesity. Dysfunctional parasympathetic nervous system activity has been proposed as one mechanism underlying alterations in energy metabolism. Arterial spin labelling (ASL) is a non-invasive MRI technique that quantifies brain tissue perfusion as a proxy for functional activity. Here, we measure cerebral perfusion in patients with ...