hrp0098p2-208 | Multisystem Endocrine Disorders | ESPE2024

A Case of Kearns-Sayer Syndrome Presenting with Hypoglycaemia and Adrenal Insufficiency

Paul Sandipan , Anne Jones Stephanie , Louca Christina

Background: Hypoglycaemia is a common critical condition in paediatric emergencies, with diverse aetiologies including metabolic disorders and endocrine dysfunctions. Adrenal insufficiency is a life-threatening cause, that requires prompt diagnosis and intervention. This case study presents a rare incidence of hypoglycaemia secondary to adrenal failure in a paediatric patient with Kearns-Sayre Syndrome (KSS), a mitochondrial disorder affecting multiple systems...

hrp0098p3-226 | Pituitary, Neuroendocrinology and Puberty | ESPE2024

Evaluation of service provision for patients with Precocious Puberty in a District General Hospital

Louca Christina , Mejeha Ijeoma , Cox Karen , Jain Gunjan , Jones Stephanie , Matei Cristina

Background: There has been a secular increase in Precocious puberty in recent years. We have also seen an increase in referrals and confirmed cases of precocious puberty in our clinics. The suspected cased underwent a Gonadotrophin Releasing Hormone (GnRH) test (GnRH) The initiation of therapy is discussed with tertiary endocrinologist colleagues, but the treatment has been delivered locally. We have recently discussed with colleagues from pharmacy aspects rel...