hrp0089p1-p266 | Thyroid P1 | ESPE2018

Childhood Thyroid Autoimmunity and Relation to Islet Autoantibodies in Children at Risk for Type 1 Diabetes

Jonsdottir Berglind , Larsson Christer , Jonsson Ida , Lundgren Markus , Larsson Helena

Background: The aim was to determine prevalence and age at seroconversion of thyroid autoimmunity and relation to islet autoantibodies, gender and HLA-DQ genotypes in children followed from birth because of increased genetic risk for type 1 diabetes.Methods: In 1874 10-year-old children followed in the Diabetes Prediction in Skåne (DiPiS) study, blood samples were analysed for autoantibodies against thyroid peroxidase (TPOAb), thyroglobulin (TGAb), ...