hrp0086lbp13 | (1) | ESPE2016

Hyperprolactinemia in Children and Adolescents: A Review of Patients Presenting to a Tertiary Center in Australia

Vora Komal , Ambler Geoffrey , Maguire Ann

Background: Hyperprolactinemia can be physiological or due to a pharmacological/pathological cause. It is relatively rare in childhood and poorly described in the literature.Objective and hypotheses: The aim of this study was to retrospectively evaluate the etiology, clinical findings and management of hyperprolactinemia in children.Method: We reviewed the records of 91 children with hyperprolactinemia (Prolactin level >760 mU/...

hrp0097p1-518 | Growth and Syndromes | ESPE2023

Outcomes of growth hormone treatment in children with Prader Willi Syndrome over a 30-year period at the Children’s Hospital at Westmead, New South Wales Australia

Gamage Dilhara , Chan Albert , Maguire Ann , Srinivasan Shubha , Ambler Geoffrey , Hi Cho Yoon

Background: Prader-Willi syndrome (PWS) is a rare genetic obesity syndrome associated with relative growth hormone deficiency. Scoliosis is a known association of both PWS and growth hormone therapy (GH), although its role in causation remains uncertain. In the literature, short-term and long-term data revealed no adverse effects of GH on scoliosis. As the metabolic and clinical benefit of growth hormone therapy is established in the management of PWS, it is d...

hrp0086lbp12 | (1) | ESPE2016

An Analysis of Symptoms and Signs of Adrenal Insufficiency in Children with CAH Admitted to Hospital in Australia

Chrisp Georgina , Maguire Ann , Quartararo Maria , Falhammar Henrik , Hameed Shihab , King Bruce , Munns Craig , Torpy David , Rushworth R. Louise

Background: An adrenal crisis (AC) is a life-threatening complication of congenital adrenal hyperplasia (CAH). Despite modern therapies, children with CAH still present with symptomatic adrenal insufficiency (AI) and AC.Objective and hypotheses: The aim of the study was to determine the spectrum of symptoms and signs of AI in children with diagnosed CAH who were admitted to hospital for an acute illness, as well as to evaluate the use of stress dosing an...