hrp0092p2-265 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Hormonal Assessment of Malformation Syndromes Associated with Disorders of Sex Development: Case Series of 9 Patients

Mahfouz Shaymaa , Abdelmeguid Yasmine

Introduction: Disorder of sex development (DSD) is a challenging condition confronting the patients, their relatives and the clinicians. It is more challenging when this disorder is associated with other extra-genital malformations. This makes their overall management more complex than if they just had DSD. Moreover, some of them have disturbed testicular function.Aim of the work: this work aimed at clinical review of 9 ...

hrp0092p2-273 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Spectrum of Genital Abnormalities in Robinow Syndrome: Case Series

Mahfouz shaymaa , Marzouk Eman

Introduction: Robinow syndrome is a rare genetic disorder characterized by mesomelic dwarfism, characteristic facial features, skeletal abnormalities and external genital abnormalities. Genital abnormalities may be noted in these patients and may cause confusion in gender assignment. In males, the characteristic pattern is micropenis with or without cryptorchidism, webbed penis or hypoplastic scrotum. In females, the anatomical defect is not always evident.The...

hrp0092p3-18 | Adrenals and HPA Axis | ESPE2019

The Unusual Adverse Side Effects of Super-Potent Topical Steroids

Abdelmeguid Yasmine , Mahfouz Shaymaa

Background: Topical steroids are commonly used in clinical practice for management of dermatological diseases. Clobetasol propionate is the most potent. They are systemically absorbed and may cause adverse side effects due to improper and prolonged use, such as iatrogenic Cushing's syndrome and adrenal insufficiency due to suppression of hypothalamic-pituitary-adrenal axis.Case presentation: A 7-month-old boy referre...